Understanding Crohn’s Disease

Symptoms, Causes & Infusion Therapy in Riyadh

What is Crohn’s Disease?

Crohn’s disease is a chronic immune-mediated inflammatory bowel disease (IBD) that causes inflammation anywhere in the digestive tract, most commonly the terminal ileum and cecum. The inflammation can extend through the full thickness of the intestinal wall, potentially leading to complications such as fistulas, abscesses, strictures, and bowel obstruction.

Early diagnosis and treatment are essential to prevent long-term complications and maintain quality of life.

Common Symptoms of Crohn’s Disease

Symptoms vary depending on the location and severity of inflammation and may include:

Persistent diarrhea (sometimes bloody, especially with colonic involvement)

Fatigue and weakness

Weight loss and reduced appetite

Blood in stool

Abdominal pain and cramping

Nutritional deficiencies (iron, B12, folate, vitamin D, calcium)

Because it is a chronic autoimmune disease, Crohn’s tends to alternate between flare-ups and remission.

What Causes Crohn’s Disease

The exact cause of Crohn’s disease is unknown, but several factors are associated with increased risk:

Immune System Dysregulation

abnormal immune response targeting the gut

Genetic Predisposition

Family history of IBD or autoimmune conditions; mutations in genes like NOD2/CARD15

Environmental Factors

Smoking, Certain Infections, and Other Triggers That May Exacerbate Inflammation

Crohn’s disease commonly has two age peaks: young adults (15–30 years) and older adults (50–70 years).

Every treatment protocol is tailored to the patient specific conditions

Managing Crohn’s with Infusion Therapy

At IV One Health, a licensed outpatient infusion clinic in Riyadh, we provide specialized infusion services to help patients manage Crohn’s disease effectively.

Crohn’s Disease Infusion Therapy Includes:

Biologic drug infusions (targeting proteins in the immune system to reduce inflammation) which include monoclonal antibodies like:
- Anti-TNF therapy e.g. Infliximab adalimumab, certolizumab to maintain remission and promote healing of the intestinal lining
- Anti-Integrin Agents e.g. Vedolizumab
- Anti-IL-12/23 Agents e.g. Ustekinumab “ the initial infusion then it can be SQ”

Our expert team ensures that every infusion therapy is delivered safely and comfortably, in a setting designed for people living with chronic diseases.

Benefits of Infusion Therapy

Reduces abdominal pain and diarrhea
Promotes healing of the intestinal lining
Prevents long-term complications such as strictures and fistulas
Improves energy, nutrition, and overall quality of life

All infusions are delivered in a safe, outpatient setting with expert monitoring and compassionate care tailored to patients living with chronic illness.

How long is Crohn’s therapy?

IV One Health provides more than treatment. We offer compassionate care tailored to each patient’s journey. Explore our Chronic Illness Infusion Services and discover how infusion therapy can improve your quality of life.

Understanding Crohn’s Disease

Symptoms, Causes & Infusion Therapy in Riyadh

What is Crohn’s Disease?

Common Symptoms of Crohn’s Disease