Understanding Ulcerative Colitis

Symptoms, Causes & Infusion Therapy in Riyadh

What is Ulcerative Colitis?

Ulcerative colitis (UC) is a chronic immune-mediated inflammatory bowel disease (IBD) that causes inflammation and ulceration in the innermost lining of the colon and rectum. Unlike Crohn’s disease, UC is limited to the colon and primarily affects the mucosal and submucosal layers.

Symptoms often occur in cycles of flare-ups and remission, ranging from mild to severe. Early diagnosis and treatment are critical to controlling inflammation, preventing complications, and improving quality of life.

Common Symptoms of Ulcerative Colitis

Symptoms vary depending on the location and severity of inflammation and may include:

Chronic diarrhea, often with blood or mucus

Urgency to pass stool and tenesmus (feeling of incomplete evacuation)

Weight loss and reduced appetite

Weight loss and reduced appetite

Abdominal pain and cramping

Fatigue and weakness

Rectal pain or bleeding

Nutritional deficiencies (iron, vitamin B12, folate, vitamin D)

Because UC is a chronic immune-mediated inflammatory disease, symptoms often come in cycles of flare-ups and remission.

What Causes Ulcerative Colitis?

The exact cause of UC is not fully understood, but several factors increase risk:

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Immune dysregulation

Abnormal Immune Response Targeting the Colon

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Genetic predisposition

Higher Risk if a First-degree Relative Has IBD

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Environmental triggers

Infections, Smoking, and Other Factors That May Exacerbate Inflammation

UC is commonly diagnosed in young adults (15–30 years) and can also present in older adults (50–70 years).

Every treatment protocol is tailored to the patient specific conditions

Infusion Therapy for Ulcerative Colitis

At IV One Health, we specialize in outpatient infusion treatments to deliver biologics and chemotherapy  for multiple conditions including oncology cases , autoimmune conditions e.g. SLE, ulcerative colitis,crohns and MS . 

Our center delivers evidence-based therapies aligned with international and national guidelines, with the goal of controlling inflammation, minimizing flare-ups, and supporting patients in achieving sustained long-term remission

Ulcerative Colitis Infusion Options:

  • Infliximab (Remicade): Anti–TNF-α monoclonal antibody; intravenous infusion.
  • Vedolizumab (Entyvio): Anti–α4β7 integrin monoclonal antibody (gut-selective); intravenous infusion.
  • Ustekinumab (Stelara): Anti–IL-12/23 (p40 subunit) monoclonal antibody; initial intravenous infusion then subcutaneous.
  • Mirikizumab (Omvoh): Anti–IL-23 (p19 subunit) monoclonal antibody; intravenous infusion then subcutaneous.

Every infusion is administered by licensed clinicians in a calm, patient-centered environment. Our goal is not just symptom management, but long-term improvement in quality of life.

Why should you Choose IV One for IV Therapy?

  • Licensed outpatient infusion center in Riyadh
  • Evidence-based IV therapy protocols following international and national guidelines for autoimmune and immune-mediated diseases
  • Patient-centered environment designed for comfort and long-term chronic care needs
  • Compassionate, specialized team trained to provide both medical expertise and emotional support
  • Flexible scheduling to accommodate patient needs
  • Reduced waiting times ensuring timely and efficient care
  • Private infusion suites to enhance comfort and minimize the risk of exposure to infections

Every treatment protocol is tailored to the patient specific conditions

At IV One Health, we understand that ulcerative colitis care is more than just medication. It’s about restoring balance, comfort, and confidence in daily life. Explore our Gastrointestinal Infusion Treatments today.

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